The Holo-Apoptosome: Activation of Procaspase-9 and. – · To estimate the size of the disk, we visualized pc-9 CARD apoptosomes by rotary metal shadowing after freeze-fracture and etching (Heuser, 1989) (Supplemental Experimental Procedures). In top views, a strongly contrasted, disk-like feature is visible above the platform (Figure 1B, white arrows). The disk had a diameter of approximately 100 Å (after correcting for the metal coating) and was.
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Backtracks Heuser – Valoanmelbournefl – Laura Heuser (pictured with fellow graduate student Mark Carroll) is in her third and last year in the department. For my Master’s thesis, I looked for possible effects that an octopamine agonist has on nestmate recognition in the honey bee. halogen infrared spot irs.
The holo-apoptosome: activation of procaspase-9 and. – · When Asp315 is cleaved, flexible L2 and L2 ends of the p20-p10 linker may move laterally, allowing the catalytic domains to interact more efficiently with the hub. The p20-p10 loop also backtracks from Asp315 into the active site where it anchors the catalytically active Cys285 (Figure S6, right). Thus, changes in this region induced by binding and auto-processing of the p20-p10 loop could.
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